November 27 - Brent Guppy

Presenter: Brent Guppy, PhD student with Dr. Kirk McManus
Title: Characterizing the Spatial and Temporal Dynamics of RNF20 in Colorectal Cancer
Date: Wednesday, November 27, 2013
Location: Theatre A “Mezzanine”
Time: 12:15 – 1:15 pm
Learning objectives:
- Define the differences between histone mono-ubiquitylation and protein poly-ubiquitylation
- Discuss how aberrant histone H2B ubiquitylation may lead to tumorigenesis
- Describe the trans-histone pathway

Dec 3 - Digital PCR presentation by Bio-Rad

10:00 - 11:00
Thompson Room
Bio-Rad presentation on their new digital PCR system by Eugene Chomey

Nov 22 - LOI for Infrastructure and Applied/Basic/Clinical CancerCare Manitoba Foundation grants

For the Infrastructure Grant Competition and the Applied/Basic/Clinical Scientist Award Competition, the Letters of Intent (LOI) must be presented to your respective Provincial Director on or before Friday, November 22, 2013. A copy of the LOI MUST be submitted at the same time to the Research Office - ON5008 or Ashley.Sitarz@cancercare.mb.ca

Dec 2 - Cell Biology Club

Dec 2- Project updates by Post Doctoral Fellow Christine Bruce & MD/PhD Alex Kuzyk
2:00 - Arnold Greenberg Lecture Theatre

Nov 25 - GCCRD Basic Imaging Workshop

Nov 25 - 29 Thompson Room
TOPICS COVERED:
-Basic Microscopy, Live Cell Imaging, Digital Imaging and Documentation, Automated Sample Analysis
-Fluorescent Dyes, Probes, Instruments, Platforms and Applications
-Fluorescent in situ Hybridization, Different Types and Applications
-Introduction to Human Cytogenetics
-FISH experiments, Imaging of Samples, Data Analysis and Discussion, Journal Clubs.

Nov 18 - Cell Biology Club

Nov 18 - Project update by PhD Candidates Brent Guppy & Yuequin Zhou
2:00 - Arnold Greenberg Lecture Theatre

Nov 6 - BMG Departmental Seminar

Presenter: Yueqin Zhou, PhD student with Dr. Geoff Hicks
Title: ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
Date: Wednesday, November 6, 2013
Location: Room 626 BMSB
Time: 12:15 – 1:15 pm
Learning objectives:
1. Understand the importance of studying FUS regulated RNA processing and its association with ALS.
2. Describe the autoregulation of FUS by alternative splicing.
3. Discuss the potential association between the compromise of FUS autoregulation and the pathogenesis of ALS with FUS mutation, and its therapeutic implication.