Dec 3 - Departmental Seminar

Presenter : Yi Yan –Ph.D. Student with Dr. Etienne Leygue
Date: Wednesday, December 3, 2014
Time: 12:15 – 12:45 pm
Location: Theatre A “Mezzanine” (2nd floor BMSB, to your right and across the hall)
Seminar Title: The bi-faceted SRA/SRAP system regulates cancer cell migration/mobility.
Learning Objectives:
• SRA/SRAP: Bifaceted Genetic System
• Approach to differentiate SRA RNA or SRAP function
• Live cell mobility assay

December 1 - Cell Biology Club

Dieter Hettig Award
Prior to today's Cell Biology Club, Sophia Shin from AstraZeneca and CancerCare Manitoba Foundation will present the recipient of the Dieter Hettig Award with a $2,000 scholarship.

Time: 2:00 pm - 3:00 pm
Place: Arnold Greenberg Lecture Theatre - ON2134
Presenter 1: Sumanta Chatterjee
Presenter 2: Pratima Basak

Nov 26 - Career Development Workshop

Date: November 26
Time: 3:00 - 4:00
Location: BMSB Theatre A
Speaker: Dr Sachin Katyal
Topic: Developing and tailoring your CV for today's job market

Nov 21 - Pharmacology Seminar

Date: Friday, November 21, 2014.
Time: 12:00 Noon
Location: S211 Medical Services Building
Topic: "Targeting metabolic dependencies in Chronic Lymphocytic Leukemia."
Speaker: Dr. Versha Banerji

For more information:
Dr. Vernon Dolinsky
Seminar Series Coordinator
vdolinsky@mich.ca

Nov 17 - Cell Biology Club

Presenter #1: Vasudeva Bhat (Raouf lab)
Presenter #2: Laura Thompson "Evaluating CIN genes in colorectal cancers" (McManus lab)
Time: 14:00 - 15:00
Location: CCMB Lecture theatre

Nov 12 - GCCRD presentation

Presenter: Dr. Ludger Klewes

Topic: GCCRD (Core Facility) capabilities and opportunities the core facility has to offer.

Date: Wednesday, November 12th

Time: 1:30-2:30pm

Location: 341 BMSB

Nov 6 - Senior Scientist Lecture

Presenter: Dr. Wayne Xu
Date: Thursday, November 6th
Time: 11:00 - 12:00.
Location: CancerCare Lecture Theatre
Title : “Cancer Biomarker Discovery".

Nov 5 - Dr Stephen Robbins & CIHR

Presenter: Dr. Stephen Robbins from CIHR
Date: Wednesday, November 5th
Time: 11:00 - 12:00.
Location: CancerCare Lecture Theatre
Title: "An update from the CIHR Institute of Cancer Research: building to 2020".

Nov 5 - BMG Departmental Seminar

Presenter: Sanzida Jahan - Ph.D. student with Dr. Jim Davie
Date: Wednesday, November 5, 2014
Time: 12:15 – 1:15 pm
Location: Theatre A “Mezzanine”
Seminar Title: Protein arginine methyltransferases (PRMTs) and Transcriptionally Active Chromatin Domains
Learning Objectives:

1. Discuss the role of Protein arginine methyltransferase in higher order chromatin structure
2. Delineate chromatin domain and barrier element
3. Explore the mechanisms that maintain chromatin domain structure

Oct 22 - BMG departmental seminar

Presenter: Laura Thompson - Ph.D. student with Dr. Kirk McManus
Date: Wednesday, October 22, 2014
Time: 12:15 – 1:15 pm
Location: Theatre A “Mezzanine” (2nd floor BMSB, across from the elevator and on your right)
Seminar Title: A High-Content Screen to Identify Novel Chromosome Instability Genes

Learning Objectives:
· Define chromosome instability (CIN) and discuss the importance of CIN gene identification
· Describe the assays developed in this study
· Explain how CIN assays are utilized for high-content screening and why gene validation is required

Nov 3 - Cell Biology Club

CCMB Lecture Theatre
2:00 - 3:00
Rebecca Dielschneider - "Targeting susceptible signaling pathways in CLL"
Chrissie Bruce - "mTOR/ERd interaction in breast cancer cells"

October 23- Laurence Pelletier

Terry Fox Research Institute presents Dr Laurence Pelletier
"Centrosome Biogenesis and the function in human cells"
CCMB Lecture Theatre
10:30 - 11:30

October 24 - Mary Marko's retirement party

We bid a fond farewell and wish Mary a relaxing (and well earned) retirement.
2:30 - 4:00
Thompson Room

Oct 6 - Cell Biology Club

Presenter: Iris Gehrke, postdoctoral fellow in Dr Versha Banerji's lab
Title: FK866 in Chronic Lymphocytic Leukemia
Location: 2nd floor lecture theatre
Time: 2:00 - 2:30

Sept 26 - 28, MICB Annual Retreat

Guest speakers
Dr. Ann Chambers,
Oncology Distinguished Scientist, Canada Research Chair in Oncology, London Regional Cancer Program, LHSC
Title: "Tumor metastasis and dormancy: lessons from experimental studies and implications for cancer patients"

Dr. Sean Egan,
Senior Scientist, Developmental & Stem Cell Biology, Professor, Department of Molecular Genetics, SickKids
Title: "Using mice to model metastasic breast cancer in humans"

Presentations also by
Sumanta Chatterjee, Vasudeva Bhat, Yongqiang Chen, Iris Gerhke, Dilshad Khan, Brent Guppy, Pratima Basak, Rebecca Dielschneider, Julius Awe

Sept 24 - Departmental Seminar

Presenter: Brent Guppy, PhD student with Dr. Kirk McManus
Date: Wednesday, September 24, 2014
Time: 12:15 – 1:15 pm
Location: Theatre A 'Mezzanine' (2nd floor BMSB, across from the elevator and on your right)
Seminar Title: Mitotic Increases in Di-methylated Lysine 79 of Histone H3 are Required for Genome Stability in Human Cells and Occur Independently of Mono-Ubiquitinated Histone H2B

10th annual CLL Meeting

The 10th Canadian CLL Meeting will be held at the Inn at the Forks on Thursday, September 18th - Friday September 19th.
This year's key note speaker - Dr Michael Keating from MD Anderson.
More information at www.cllmeeting.ca

Aug 1 - MSc Oral Defense Aleksander Ilic

M.Sc. Oral Defence – Aleksander Ilic, M.Sc. student with Dr. Jim Davie
Title: Role of UCHL1 In Regulation of Gene Expression in Prostrate Cancer Cells
Date: Friday, August 1, 2014
Time: 10:00 AM
Place: 341 Basic Medical Sciences Bldg.

Sept 26 - 28th MICB Annual Retreat

September 26-28th - MICB Annual Retreat at the Lakeview Resort and Conference Center in Gimli, Manitoba.
This year's theme is "Metastasis and Relapse" with Ann Chambers and Sean Egan as our invited speakers.

Deadline for registration is August 29th with Cecile Verrier.

A sign-up sheet is posted at the office for those who require or are willing to provide transportation to the Lakeview Resort.

August 31 - Deadline for Simon and Sarah Israels Graduate Thesis Prize

August 31 - Deadline to apply for Simon and Sarah Israels Graduate Thesis Prize worth $2000

Graduate student must have:
- supervisor much hold appointment as Senior Scientist or Research Affiliate Scientist at the MICB
- successfully completed a MSc or PhD at the University of Manitoba between Sept 2013 - Aug 2014

Please speak to Cecile Verrier for more details.

August 15th - MICB/BMG Annual Barbeque

August 15
12:00 - 4:00
2015 Main Street, Kildonan Park
This is a potluck. Please sign up at the front office to bring food.
Spouses and kids are welcome to join.
Remember to bring a football or frisbee, suntan lotion, chair and mosquito repellent.

August 20th - MICB Summer Student Symposium

Arnold Greenberg Lecture Theatre
9:00 - 1:00
Coffee and donuts at 10:15
Presentations by our undergraduate students to discuss the results of their summer research projects.

"My Science Journey: Reflections & Tips for Success from a former MICB summer student"
Guest speaker at 11:45 by Dr Meghan Azad,
Assistant Professor, Department of Pediatrics & Child Health
Research Scientist, Manitoba Institute of Child Health
Knowledge Synthesis Manager, Centre for Healthcare Innovation

Recruiting trainees for Katyal lab

Dr Sachin Katyal is recruiting a post-doctoral fellow to look at DNA damage repair responses in the development of novel cancer therapeutic strategies. The lab is CIHR and MHRC funded and offers an exciting research intensive training environment with ample opportunity for growth and development.
MSc students with prior research training are preferred.
Postdocs with a minimum of 1-2 research publications are preferred.

Sachin.Katyal@umanitoba.ca
http://umanitoba.ca/faculties/medicine/units/pharmacology/

June 19 - Annual State of the Institute Talk by Dr Gibson

June 19th
11:00 - 12:00
CCMB Lecture Theatre
Dr Gibson will be providing his annual State of the Institute lecture.
Everyone is strongly encouraged to attend.

June 13 - Imaging Symposium celebrating the 15th Anniversary of the Genomic Centre

IMAGING SYMPOSIUM
GCCRD 15th Anniversary
June 13, 2014
8:00am - 7:00pm
Guest speakers from Thailand, Arizona, the Netherlands, Germany, Montreal, Maryland, Sweden, Vancouver and Winnipeg
Arnold H Greenberg Lecture Theatre – ON2134 CancerCare Manitoba

May 12 - Cell Biology Club

The scheduled presenters are: Amy Dahl and Bernardino Petrelli
Time: 2:00 pm - 3:00 pm
Place: Arnold Greenberg Lecture Theatre - ON2134

June 3 - 10th Annual Dr. Lyonel G. Israels Memorial

Tuesday, June 3, 2013 ~ 12:00 – 1:00 pm
CancerCare Manitoba Lecture Theatre (ON2134)
Invited Speaker Dr. Helen Heslop
Center for Cell and Gene Therapy
Baylor College of Medicine
Houston, Texas
~~~~~~~~~~~~~~~~
“Immunotherapy with Antigen Specific T Cells”
~~~~~~~~~~~~~~~~

May 16 - PhD Thesis Defense

May 16 at 10:00
Room 626 Basic Medical Sciences Building
Yueqin Zhou
"Dysregulation of FUS dependent RNA Metabolism is a Central Mechanism Underlying ALS and Cancer Pathogenesis"

May 8 - CCMB Research Day

May 8th - 16th annual CancerCare Manitoba Research Day for Trainees in Clinical & Basic Sciences
Dr Lillian Siu, Medical Oncologist from Princess Margaret Cancer Centre will be the guest judge and lunch time speaker.
Oral and poster presentations will be judged and awards will be given for best Basic Sciences and Clinical.

May 15th - Visiting Professor

May 15th
Dr. Keith Bonham
CCMB Lecture Theatre
1:00 - 2:00
"Epigenetic reprogramming in cancer: A tale of two Kinases".
Students, RA’s and PDF’s are invited to meet and have lunch with Dr. Bonham in the Thompson Room prior to his talk.

May 23 - MICB Research Seminar Dr Deepa Sampath

Friday, May 23rd at 11am
Arnold Greenberg Lecture Theatre.
Dr. Deepa Sampath presents "Epigenetic modulation of miRNA in CLL".
Students, RA’s and PDF’s are invited to meet and have lunch with Dr. Sampath following her talk. The luncheon will be held in the Thompson Room (ON6007) at noon.

June 13 - Imaging Symposium celebrating the 15th Anniversary of the Genomic Centre

IMAGING SYMPOSIUM
GCCRD 15th Anniversary
June 13, 2014
8:00am - 7:00pm
Guest speakers from Thailand, Arizona, the Netherlands, Germany, Montreal, Maryland, Sweden, Vancouver and Winnipeg
Arnold H Greenberg Lecture Theatre – ON2134 CancerCare Manitoba

April 28 - Cell Biology Club

Special Presentation by Dr Rashid Ahmed (Epidemiology and Population Health)
followed by project updated by Tarek Bader
CancerCare Lecture Theatre
2:00 - 3:00

April 14 - Cell Biology Club

Project update by Oumar Samassekoum
April 14
2:00 - 2:30
CancerCare Lecture Theatre

April 28 - Edge of Science Seminar

"High risk Hodgkin's lymphoma identified by 3D telomere analysis of chromosomal instability"
April 28 12:00 - 1:00
Frederick Gaspard Theatre (C)
Basic Medical Sciences Building
Dr Donna Wall and Dr Sabine Mai

April 24 - Application deadline for CCMB Research Day for Trainees

The deadline to submit your application for either a poster or an oral presentation is April 24th.

Abstracts must use the following categories:
1) Objectives
2) Methods
3) Results
4) Conclusions

Abstracts must be formatted as:
- maximum of 300 words, single spaced using 11pt Times New Roman font
- 1" block and justified margins
- All results and conclusions must be stated in the abstract

Submit via email to Jaclyn.Javier@cancercare.mb.ca

April 1 - Haematology/Oncology Regional Grand Rounds

Title: The Cancer Community: Everyone Counts.
Presented by: Dr. Shantanu Banerji, Medical Oncologist
Time: 12:00 - 1:00
Location: CCMB Lecture Theatre
Educational Objectives: Define intra-tumour heterogeneity, appreciate the rationale for exploring tumour heterogeneity

March 31 - Cell Biology Club

Project updates by Landon Wark, Eric Bouchard & Laura Thompson
2:00 - 3:00
CCMB Lecture Theatre

April 2 - PhD Thesis Defense for Sara Beiggi

Notice of Final PhD Oral Examination for Sara Beiggi
Department of Biochemistry & Medical Genetics
“Epidemiological Study of Chronic Lymphocytic Leukemia (CLL) in the Province of Manitoba, Canada”
DATE: WEDNESDAY, APRIL 2, 2014
TIME: 10:00 A.M.
PLACE: 341 BASIC MEDICAL SCIENCES BLDG.

March 19 - BMG Departmental Seminar

Presenter: Dr. Versha Banerji, Department of Internal Medicine & Biochemistry and Medical Genetics
Date: Wednesday, March 19, 2014
Time: 12:15 – 1:15 pm
Location: Theatre A “Mezzanine”
Seminar Title: "Inhibiting Nicotinamide phosphoribosyl transferase (NAMPT) to kill Chronic Lymphocytic Leukemia cells"

March 6th - Genetic Academic Sessions

Location: Gordon Chown Room, Basement CSB
Research rounds: Thursday, March 6th 3:00 pm – 4:00 pm
Presenter: Yueqin Zhou, PhD candidate
Topic: “Familial ALS with FUS mutations has compromised alternative splicing and autoregulation - a mechanism of rare disease with broad implication?”

After this session, participants will be able to:
Understand the genetics bases of amyotrophic lateral sclerosis (ALS).
Describe the mechanism of FUS autoregulation through alternative splicing.
Discuss the significance of dysregulated FUS autoregulation in ALS-FUS pathogenesis and its therapeutic implication..

This event is an accredited group learning activity as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada

February 26 - BMG Departmental Seminar

Berardino Petrelli, M.Sc. Student with Dr. Geoff Hicks
Time: 12:45 – 1:15 pm
Location: Theatre A “Mezzanine”
Seminar Title: A FASD Mouse Model: Biochemically Mimicking Alcohol Exposure using Gsc promoter driven Cyp26A1 cDNA
Learning Objectives:
· Describe Fetal Alcohol Spectrum Disorder and the FASD continuum.
· Describe the clinical features of FAS in humans and explain the resultant phenotypic effects obtained in murine models of FAS.
· Explain the rationale for the molecular strategy and targeting of the CYP26A1:eGFP cassette to the Goosecoid (Gsc) locus and describe cassette validation techniques in vitro and in vivo.

March 3 - Cell Biology Club

Presentations by Sanzida Jehan
March 3rd
14:00 – 15:00
CCMB Lecture Theatre

Feb 12 - BMG Departmental Seminar

Presentation: Laura Thompson, M.Sc. Student with Dr. Kirk McManus
Date: Wednesday, February 12, 2014
Time: 12:45 – 1:15 pm
Location: Theatre A “Mezzanine”
Seminar Title: Developing a High-Content Screen to Identify Human Chromosome Instability Genes

Learning Objectives:
· Define chromosome instability (CIN) and discuss the importance of CIN gene identification
· Describe the complementary assays that are capable of detecting CIN
· Explain how CIN assays can be utilized in a high content screen of candidate genes

BIochemistry & Medical Genetics Department Seminar

Presenter: Aleksander Ilic, M.Sc. Student with Dr. Jim Davie
Date: Wednesday, February 5, 2014
Time: 12:45 – 1:15 pm
Location: Theatre A “Mezzanine”
Seminar Title: Role of UCHL1 in regulating gene expression in prostate cancer cells
Learning Objectives:
· Discuss the primary role of UCHL1 as a deubiquitinating enzyme
· Describe the UCHL1 interaction with genomic DNA and its possible role in regulating gene expression in prostate cancer
· Explain how ChIP and ChIP-seq can be utilized to map the genomic location of protein binding sites

February 3 - Cell Biology Club

February 3 - Cell Biology Club
Project updates from Sanzida Jahan and Yingfeng Zheng
2:00 - 3:00
Arnold Greenberg Lecture Theatre, 2nd floor CancerCare Manitoba

Jan 20 - Cell Biology Club

January 20th - Cell Biology Club
Project updates from Sumanta Chatterjee and Pratima Basak
2:00 - 3:00
Arnold Greenberg Lecture Theatre, 2nd floor CancerCare Manitoba

Jan 9 - Sanzida Jahan

BMG Departmental Seminar…
Presenter: Sanzida Jahan, PhD student with Dr. Jim Davie
Title: Characterization of transcriptionally active novel histone H5 chromosomal domain using avian erythrocyte cells
Date: Wednesday, January 8, 2014
Location: Theatre A “Mezzanine”
Time: 12:15 – 1:15 pm
Learning objectives:
1. To understand the higher order chromatin structure separated by chromatin boundaries.
2. To identify signatures to characterize chromatin boundaries.
3. To characterize the mechanism of maintaining open chromatin domain.