Jan 6 - Cell Biology Club

January 6 - Speaker- Lawrence Ryner, PhD, Dept of Medical Physics, CCMB
"Enhanced MRI for Cancer Assessment"

Abstract- MRI is capable of much more than exquisite images of soft-tissue. It can non-invasively probe the biochemistry of tissue, provide markers of angiogenesis, assess tumour cellularity, and much more. Dr. Ryner will review the basics of MR imaging and move on to review the additional information available for cancer assessment through enhanced MRI techniques.

Followed by a project update by Dr. Sajesh Babu (PDF)
2:00 - 3:00
Arnold Greenberg Lecture Theatre

Dec 20 - MICB Christmas party

Dec 20 at CanadInns Aalto's from 12:00 - 3:00
Please sign up at the front office before December 6th.

November 27 - Brent Guppy

Presenter: Brent Guppy, PhD student with Dr. Kirk McManus
Title: Characterizing the Spatial and Temporal Dynamics of RNF20 in Colorectal Cancer
Date: Wednesday, November 27, 2013
Location: Theatre A “Mezzanine”
Time: 12:15 – 1:15 pm
Learning objectives:
- Define the differences between histone mono-ubiquitylation and protein poly-ubiquitylation
- Discuss how aberrant histone H2B ubiquitylation may lead to tumorigenesis
- Describe the trans-histone pathway

Dec 3 - Digital PCR presentation by Bio-Rad

10:00 - 11:00
Thompson Room
Bio-Rad presentation on their new digital PCR system by Eugene Chomey

Nov 22 - LOI for Infrastructure and Applied/Basic/Clinical CancerCare Manitoba Foundation grants

For the Infrastructure Grant Competition and the Applied/Basic/Clinical Scientist Award Competition, the Letters of Intent (LOI) must be presented to your respective Provincial Director on or before Friday, November 22, 2013. A copy of the LOI MUST be submitted at the same time to the Research Office - ON5008 or Ashley.Sitarz@cancercare.mb.ca

Dec 2 - Cell Biology Club

Dec 2- Project updates by Post Doctoral Fellow Christine Bruce & MD/PhD Alex Kuzyk
2:00 - Arnold Greenberg Lecture Theatre

Nov 25 - GCCRD Basic Imaging Workshop

Nov 25 - 29 Thompson Room
TOPICS COVERED:
-Basic Microscopy, Live Cell Imaging, Digital Imaging and Documentation, Automated Sample Analysis
-Fluorescent Dyes, Probes, Instruments, Platforms and Applications
-Fluorescent in situ Hybridization, Different Types and Applications
-Introduction to Human Cytogenetics
-FISH experiments, Imaging of Samples, Data Analysis and Discussion, Journal Clubs.

Nov 18 - Cell Biology Club

Nov 18 - Project update by PhD Candidates Brent Guppy & Yuequin Zhou
2:00 - Arnold Greenberg Lecture Theatre

Nov 6 - BMG Departmental Seminar

Presenter: Yueqin Zhou, PhD student with Dr. Geoff Hicks
Title: ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
Date: Wednesday, November 6, 2013
Location: Room 626 BMSB
Time: 12:15 – 1:15 pm
Learning objectives:
1. Understand the importance of studying FUS regulated RNA processing and its association with ALS.
2. Describe the autoregulation of FUS by alternative splicing.
3. Discuss the potential association between the compromise of FUS autoregulation and the pathogenesis of ALS with FUS mutation, and its therapeutic implication.

Nov 4 - Cell Biology Club

Nov 4 - Cell Biology Club
Project update by Post Doctoral Fellow Patrapim Sunpaweravong
Starting at 2:00
Arnold Greenberg Lecture Theatre

Oct 21 - Cell Biology Club

Date: October 21
Time: 2:00 - 3:00
Location: Arnold Greenberg Lecture Theatre
Presenters: Dr Sachin Katyal (Measureing DNA damage repair mechanisms)
Followed by Rebecca Dielschneider (PhD Student - Gibson lab)

October 9 - BMG Departmental Seminar

Presenter: Alexandra Kuzyk, MD/PhD student with Dr. Sabine Mai
Title: A study of nuclear disorganization in cancer cells.
Date: Wednesday, October 9, 2013
Location: Theatre A “Mezzanine” 12:15 – 1:15 pm
Learning objectives:
· List two aspects of nuclear architecture.
· Describe the relationship between nuclear localization and transcription.
· Explain the 11E2 and 17q25 synteny region and their impact in mouse plasmacytoma and human neuroblastoma

Oct 2 - Visiting Speaker

October 2 - 2:00-3:00
CCMB Lecture Theatre
Dr Asish K. Ghosh
Assistant Professor of Medicine, College of Medicine
Mayo Clinic
"Microvesicle Mediated Crosstalk in B-Cell Chronic Lymphocytic Leukemia: Implications in Disease Progression"

Sept 18 - Visiting Speaker Dr Freda Miller

Neural Stem Cells: From Development to Repair
Visiting Speaker Dr. Freda Miller
CRC Developmental Neurobiology
University of Toronto and Sick Kids Research Institute
Time: 12:15 – 1:15 pm
Location:** Apotex Centre, Room 264 (Pharmacy Bldg.)

Cell Biology Club 2013/2014 Starts September 23rd

Please remember to sign up for your spot in Cell Biology Club before August 30th or a spot will be assigned to you.

Post-doctoral fellows and PhD student are allocated 20 minutes (15 minutes for presentation, 5 minutes for discussion) starting in September. MSc students are allocated 15 minutes, starting in January.

Presentations are focused on recent data with special emphasis on the last 2-4 months of research.
Presentations will be concise with a brief introduction to your project, most recent data, problem(s) you encountered, what you did to overcome these problems and the data that resulted. Trainees are expected to present all recent data, including positive and negative results, in order to generate discussion from audience members.

August 23 - MSc Oral Defence Jennifer Schacter

Title: ESTROGEN REGULATION OF ANTI-APOPTOTIC BCL-2 FAMILY MEMBER MCL-1 EXPRESSION IN BREAST CANCER
Date: Friday, August 23, 2013
Time: 9:30 AM
Place: 626 Basic Medical Sciences Bldg.

August 31st - Deadline for Simon and Sarah Israels Graduate Thesis Prize

The Simon and Sarah Israels Graduate Thesis Prize is an award of $2,000 for the best thesis submitted by a Graduate student at MICB.

Eligibility: All Graduate students whose supervisors hold appointments as a Senior Research Scientist or Research Affiliate Scientist at MICB and who have successfully completed a program of studies leading to a Master or Ph.D. degree at UofM in Sept 2012 - Aug 2013.

Submit three unbound copies to Cecile by August 31st.

August 15th - Dilshad Khan PhD Oral Defense

Title: Role of Histone Deacetylases in Gene Expression and RNA Splicing
Date: Thursday, August 15, 2013
Time: 9:00 AM
Place: 341 Basic Medical Sciences Bldg

August 15th - Dr Philippe Georgel

August 15th 2:00 - 3:00
Dr Phillipe Georgel
Professor, Department of Biological Sciences
Cell Differentiation and Development Center
Byrd Biotechnology Science Center
Marshall, University
"Investigating the complex interplay between diet, epigenetics and cancer"
CCMB Lecture Theatre

August 23 - MICB Annual BBQ Potluck

Friday, August 23rd, 11:30 am – 4:00 pm
Kildonan Park - 2012 Main Street. Exact picnic site to be determined.
RSVP by August 19th.

This is a family event so your spouse and kids are invited too.
Please sign up with what you will be bringing for the potluck and the number of guests.
BMG/MICB will be supplying the hamburgers and hotdogs.

Come out and enjoy the food and fellowship!

August 31 - Simon and Sara Israels Graduate Thesis Prize

All Graduate students whose supervisors hold appointments as a Senior Research Scientist or Research Affiliate Scientist at the Manitoba Institute of Cell Biology and who have successfully completed a program of studies leading to a Master or Ph.D. degree at the University of Manitoba in the year prior to the granting of the award (Sept 2012 - Aug 2013) are eligible for this $2000 prize.

Submit an unbound copy to Cecile Verrier in the main office.

July 5 - Tell us how Cell Biology Club was

Based on meetings we had with staff and trainees last year, we re-vamped Cell Biology Club. We would like to know what you think about these changes. The deadline to submit your opinions and suggestions on how to improve it is July 5th.

http://www.surveymonkey.com/s/B88HJ78

July 8 - Cell Biology Club

A special presentation by Dr Rhea Vallente about the Genomic Centre for Cancer Research and Diagnosis (GCCRD).
July 8 at 2:00 in the Lecture Theatre.

June 13 - Seminar by Dr Ryan Zarychanski

"The HALO Study - meta-analysis of hydroxyethyl starch in the ICU"
Greenberg Lecture Theatre
11:00 - 12:00

June 20th - State of the Institute talk

Dr Spencer Gibson will be giving his annual State of the Institute talk on June 20th from 11:00-12:00 in the Greenberg lecture theatre.
The first annual MICB Merit Award will be presented to in appreciation of the contributions of MICB staff member, as nominated by you!
Donuts and coffee will be provided.

June 3 - Cell Biology Club

Special presentation on FACS by Armando Poeppl
Followed by a project update by Brent Guppy.
Time: 2:00 pm - 3:00 pm
Place: Arnold Greenberg Lecture Theatre - ON2134

May 27 - Cell Biology Club

The scheduled presenters are: Alexsandar Ilic and Amy Cisyk.
Time: 2:00 pm - 3:00 pm
Place: Arnold Greenberg Lecture Theatre - ON2134

May 28 - Ju-Yoon Yoon PhD Thesis Defense

Ju-Yoon Yoon, PhD Oral Examination for Biochemistry and Medical Genetics
"Elderly patients with Chronic Lymphocytic Leukemia: Predicting their survival and managing their disease with Valproic Acid and Fludarabine"
Time: 2pm
Place: Thompson Room (ON6005)

May 13 - Cell Biology Club

Special Presentation by Dr Arzu Ozturk on the process of developing a knock-out mouse, followed by a project update by Oumar Samassekou.
2:00 - 3:00 CCMB Lecture Theatre

May 30 - Dr. Ryan Zarychanski

11:00 am – 12:00 pm – ON2134
"The use of anticoagulants to modulate host inflammation in sepsis: The HALO research program"
Dr. Ryan Zarychanski, MD. MSc.
Assistant Professor, University of Manitoba,
Sections of Hematology/Medical Oncology and Critical Care

May 28 - Dr David Spaner

10:30 – 11:30 pm – ON2134
"Nuclear receptors and fatty acid oxidation as therapeutic targets for Chronic Lymphocytic Leukemia"
Dr. David Spaner, M.D. Ph.D.
Senior Research Scientist
Sunnybrook Research Institute

May 16 - Dr Stephen Pistorius

11:00 am – 12:00 pm – ON2134
"Turning Noise into Numbers: Progress in using scattering to improve diagnostic imaging"
Dr. Stephen Pistorius, Ph.D. M.Sc.
Senior Research Scientist, CancerCare Manitoba
Director: Medical Physics Academic Program
Vice Director: Biomedical Engineering Graduate Program
Professor: Physics and Astronomy, U of M
Associate Professor: Radiology

May 8 - Dr Christine Vande Velde

11:00 am – 12:00 pm ON2134
"The Cell Biology of Lou Gehrig's Disease"
Dr. Christine Vande Velde, Ph.D.
CIHR New Investigator
Associate Professor, Research
Department of Medicine, Universite de Montreal

May 14 - The 9th Annual Dr Lyonel G Israels Memorial Lecture

Dr. Patrick Gallagher "Genetics and Genomics of Inherited Erythrocyte Disorders"
Professor of Pediatrics (Neonatology), Genetics and Pathology
Director, Yale Center for Blood Disorders
Director, Expression and Genomics Core
Yale Center of Excellence in Molecular Hematology
~~~~~~~~~~~~~~~~
Tuesday, May 14, 2013 ~ 12:00 – 1:00 pm
Lecture Theatre (ON2134)

April 29 - Cell Biology Club

The scheduled presenters are: Jennifer Schacter, Landon Wark and Rebecca Delong
Time: 2:00 pm - 3:00 pm
Place: Arnold Greenberg Lecture Theatre - ON2134

May 6 - Edge of Science Seminar Series

Dr Michael Taylor, Hospital for Sick Children, Toronto ON.
"Molecular Heterogeneity through Space and Time Accounts for the Clinical Behaviour of Childhood Medulloblastoma"
Theatre E - Old Basic Science Building
12:00 - 1:00

April 15th - Cell Biology Club

The scheduled presenters are: Protiti Khan and Shannon Healy.
Time: 2:00 pm - 3:00 pm
Place: Arnold Greenberg Lecture Theatre - ON2134

Registration opens for CCRA Canadian Cancer Research Conference

The 2nd annual Canadian Cancer Research Conference will be taking place from Sunday Nov 3 to Wednesday Nov 6 at the Sheraton Centre Toronto Hotel in Toronto.

The conference will:
- Showcase the breadth and excellence of Canadian cancer research to both the research community and the public;
- Provide a single venue for researchers from across the cancer research spectrum and cancer sites;
- Expose researchers to new areas, new techniques, infrastructures and facilities to support cancer research;
- Allow for cross-fertilization between research disciplines;
- Provide networking opportunities for researchers at all levels of their careers.

Register at http://www.ccra-acrc.ca/index.php/registration

Research Days - New Application Deadline

Applications for the 15th annual CancerCare Research Day have been extended to April 19th. Prizes for top 3 trainee presentations in both oral and poster presentations, clinical and basic sciences. Please submit your application to Amanda Amy before April 19th to participate.

April 11 - Research Seminar Dr M Azad

Dr Meghan Azad, Former MICB PhD student now Post-doctoral fellow in the Department of Pediatrics at the University of Alberta, will be presenting "Discoveries from Dirty Diapers: Environmental Exposures and the Infant Gut Microbiome"
11:00 - 12:00 CCMB Lecture Theatre

April 18 - Annual Arnold Greenberg Lecture

Dr Benjamin Neel, Director of the Ontario Cancer Institute and internationally recognized expert in cancer biology and cellular signal transduction, will be presenting "Shp2 and its Binding Proteins in Health and Disease".
Lecture Theatre, 11:00 - 12:00 Lunch reception to follow.
Students can schedule meetings with Dr Neel after 1pm in the Executive Boardroom.

March 19 - Guest Lecture on CLL

12:00 - 1:00 Arnold Greenberg Lecture Theatre
Dr Timothy Call, consultant hematologist at the Mayo Clinic
"Management of CLL and it's Complications - 2013"

March 22 - Bioinformatics and Data Analysis

March 22 - BMG Lecture Theatre
Dr Wayne Xu, Bioinformatician, will explain the steps involved in data analysis from the NGS platform for ChIP-Seq, RNA-Seq and chromatin fractionation. He will demonstrate how raw sequence data is processed into manuscript quality figures and how to access the ENCODE (epigenetics) data.

Registration required - email Cecile Verrier by March 19th.

March 21 - CIHR Town Hall

Arnold Greenberg Lecture Theatre - tentatively scheduled for the afternoon of
University of Manitoba will be hosting a visit by Dr. Alain Beaudet, CIHR President, on March 21st to discuss the CIHR reforms. As part of this visit, there will be a town hall meeting with researchers. Please visit http://www.cihr-irsc.gc.ca/e/46371.html for more information.

Feb 28th - NGS Sequencing Analysis and Target Enrichments

Feb 28th 10:45 - 12:00 CancerCare Lecture Theatre
Agilent Target Enrichment Seminar.
This presentation features a review of SureSelect and HaloPlex technology, portfolio and applications. Updates on key new products – such as the new All Exon V5 and V5+UTRs kits –as well as solutions for NGS data analysis will also be presented.
RSVP carine.lafaille@kprime.net or angelyn_regala@agilent.com

March 18th - Cell Biology Club

Cell Biology Club on March 18th will include presentations from Yi Yan, Yueqin Zhou and Patrapim Sunawersvong.
2:00 - 3:00
Arnold Greenberg Lecture Theatre (CCMB)

February 23 - Sharing International Perspectives on FASD Research and Interventions

The Canada Israel International Fetal Alcohol Consortium is pleased to invite you to the International FASD Collaborations Symposium - Sharing international perspectives on FASD research and interventions.
at the Apotex Centre, 750 McDermot Ave.
Registration: Free! This is an open event, no registration is required.

9:00am Presentations on FASD in France Dr. Denis Lamblin, President, SAFFrance
10:15am Presentation on FASD in Finland Dr. Ilona Autti-Ramo, Chief of Health Research, Research Professor, The Social Insurance Institution, Finland
11:00am Presentation on Canada Israel International Fetal Alcohol Consortium (CIIFAC) Dr. Ab Chudley, CIIFAC Research Lead Medical Director, Program in Genetics and Metabolism, University of Manitoba

March 5th - Illumina Technology Day

March 5 2nd Floor Lecture Theatre
9:45-11:00 Advances in Cancer and Personalized Genomics Using NGS Sequencing Technology.
Speaker: Dr Michael Smith, Sequencing Specialist, Illumina Inc.

Learn how Illumina NGS technology can help you uncover the answer to drive your research forward. A simple end-to-end sequencing workflow lets you go from sample to results faster and easier than ever before. During this event, an Illumina expert will present an overview of NGS, discussing the basic concepts and key advantages over traditional technologies.

Feb 20th - Molecules, Cerebellar Development and Autism

Feb 20th, 11:00 - 12:00 Edge of Science Seminar - "Molecules, Cerebellar Development and Autism" by Dr Dan Goldowitz, Scientific Director of NeuroDevNet and Professor in the Dept of Medical Genetics UBC
Lecture Theatre C Basic Medical Sciences Building

Mar 4th - Cell Biology Club

March 4th - The next Cell Biology Club will feature a special presentation by Molly Pind on Bioinformatics followed by a project update by Dilshad Khan.
2:00 Arnold Greenberg Lecture Theatre

Feb 4th - Cell Biology Club

The next Cell Biology Club will be on February 4th with a special presentation by Michelle Brown on PCR 101, followed by a project update by post-doc Sara Beiggi.
Arnold Greenberg Lecture Theatre 2:00

Jan 29 - NGS Workshop

Jan 29 1:00 - 5:00 Executive Boardroom, 4th floor CancerCare Manitoba
A panel of academic and industry speakers experienced in NGS will provide an overview of NGS, a more detailed look at instrumentation and consumables, and hear directly from academics putting local NGS platforms to work. The workshop is open to anyone who is interested in or is already using NGS in their research or diagnostic programs. Each talk will last 20‐30 minutes, and ample time will be made available for discussion. Registration is required due to limited seats – please email rsetter@idtdna.com (604‐309‐5116)

Jan 21 - Cell Biology Club

What is Next Generation Sequencing and how can I use it for my research?
Presentation by Debbie Tsuyuki followed by Tarek Bader - Dr Murphy's lab
Arnold Greenberg Lecture Theatre
Jan 21 @ 2:00

Feb 1 - MHRC Funding Competition

Just a reminder that the MHRC Funding Competition for Studentships, Fellowships and Dissertation Awards is Feb 1. The University deadline is January 21st.
All applicants must use the CommonCV and submit their applications through GMS.
For more information, please go to http://mhrc.mb.ca

Jan 28 - CIHR Cafe Scientifique

NATURE AND NURTURE (NOT VERSUS): THE NEW SCIENCE OF EPIGENETICS
January 28, 2013 – 7:00 pm
McNally Robinson Booksellers, 1120 Grant Avenue, Winnipeg
Expert panelists Dr Jim Davie, Dr Kirk McManus, Dr Mojgan Rastegar.
Moderator Dr Peter Cattini
Seating is limited, RSVP to: Research_Communications@umanitoba.ca, (204) 474-6689

Welcome back!

Happy New Year! Hoping 2013 is the year your western blots run straight, your cells aren't contaminated, there's room in the -80 and p is less than 0.05.